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2,2′-Bipyridine (bipy or bpy, pronounced ) is an organic compound with the formula C10H8N2. This colorless solid is an important isomer of the bipyridine family. It is a bidentate chelating ligand, forming complexes with many transition metals. Ruthenium complex and platinum complexes of bipy exhibit intense luminescence, which may have practical applications.
Bipyridine is an organic heterocyclic compound containing two pyridine rings connected at one carbon site on each ring, with general formula C10H8N2. Each rings contain tri-unsaturated six-membered ring of five carbon atoms and one nitrogen atom. Bipyridine is a white solid slightly soluble in water and soluble in organic solvents. Six isomers of the simplest bipyridine exist. The rules of nomenclature would indicate the position of N atoms in the ring. Bipyridine molecules are coordinated as chelate ligands to form a complex with a transition metal ion. Bipyridines are involved in photosensitizer chemistry, luminescent materials, and metal complex chemistry. Bipyridines can be used in:
Transition-metal complex catalyst chemistry for uniform polymerization
Luminescence chemistry and spectrophotometric analysis
Organic synthesis and polymerization
Some bipyridinium molecules, quaternary ammonium compounds, are active ingredients of contact herbicides with non-selective and fast-acting properties. They are poisonous to humans also. They are readily reduced to radical ion which reacts with unsaturated membrane lipids. Pyridinium class plant protection products include cyperquat, diethamquat, difenzoquat, diquat and morfamquat.
Amrinone and milrinone, bipyridine ketone derivatives, are positive inotropic cardiotonic agents with vasodilator effects. They are phosphodiesterase inhibitor that prevents enzymatic breakdown of cyclic AMP by phosphodiesterase. They stimulate calcium ion influx into the cardiac cell. Etoricoxib, a bipyridine non-steroidal antiinflammatory drug, is a COX-2 selective inhibitor.
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